STRING-db-MCP-Server

STRING-db-MCP-Server

3.3

If you are the rightful owner of STRING-db-MCP-Server and would like to certify it and/or have it hosted online, please leave a comment on the right or send an email to henry@mcphub.com.

The STRING MCP Server is an unofficial Model Context Protocol server designed to access the STRING protein interaction database, providing tools for protein network analysis, functional enrichment, and comparative genomics.

The Unofficial STRING MCP Server is a comprehensive tool for researchers and scientists interested in protein interaction networks and functional genomics. It leverages the STRING database, a well-known resource for protein-protein interactions, to offer a suite of tools that facilitate the analysis of protein networks, functional enrichment, and comparative genomics. The server integrates with the STRING API, allowing users to access a wide range of data, including direct protein interactions, network construction, and functional annotations. With support for over 5000 organisms, the server provides multi-species analysis capabilities, making it a valuable resource for evolutionary studies and cross-species comparisons. The server also emphasizes data quality and validation, incorporating curated data and computational predictions to ensure reliable results. Additionally, it offers robust error handling to manage invalid inputs and connectivity issues, ensuring a smooth user experience.

Features

  • Protein Interaction Analysis: Direct interactions, network construction, evidence classification, and confidence scoring.
  • Functional Analysis: GO enrichment, KEGG pathways, custom backgrounds, and statistical significance.
  • Comparative Genomics: Cross-species analysis, evolutionary relationships, species filtering, and ortholog identification.
  • Network Properties: Topology analysis, hub identification, module detection, and path analysis.
  • Data Quality & Validation: Curated data, evidence integration, regular updates, and quality scores.

Tools

  1. get_protein_interactions

    Get direct interaction partners for a specific protein with confidence scores and evidence types.

  2. get_interaction_network

    Build and analyze protein interaction networks for multiple proteins.

  3. get_functional_enrichment

    Perform functional enrichment analysis using GO terms, KEGG pathways, and other annotations.

  4. get_protein_annotations

    Get detailed protein annotations and functional information.

  5. find_homologs

    Find homologous proteins across different species for comparative analysis.

  6. search_proteins

    Search for proteins by name or identifier across multiple species.