OpenTargets-MCP-Server
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The Unofficial Open Targets MCP Server provides a Model Context Protocol server for accessing data from the Open Targets platform, facilitating research on gene-drug-disease associations.
The Unofficial Open Targets MCP Server is a specialized server designed to interface with the Open Targets platform, offering researchers a streamlined way to access and analyze data related to gene-drug-disease associations. Developed by Augmented Nature, this server leverages the Model Context Protocol (MCP) to provide a robust and efficient means of querying the Open Targets API. With a focus on therapeutic targets, disease associations, and comprehensive data retrieval, the server supports a variety of research workflows, from cancer research to drug discovery. It integrates data from over 20 databases, including ChEMBL, Ensembl, and ClinVar, ensuring that users have access to a wide array of information. The server is built using TypeScript for type safety, employs GraphQL for data queries, and adheres to MCP Protocol standards for communication. It is designed to be production-ready, with features like error handling, logging, and generous rate limits for research use.
Features
- Target Search: Allows users to search for therapeutic targets using gene symbols, names, or descriptions.
- Disease Search: Enables searching for diseases by name, synonym, or description.
- Target-Disease Associations: Provides evidence scores for associations between targets and diseases.
- Disease Target Summaries: Offers prioritized therapeutic targets for specific diseases.
- Comprehensive Data Retrieval: Access detailed information on genes, proteins, and diseases.
Tools
search_targets
Search therapeutic targets by gene symbol, name, or description.
search_diseases
Search diseases by name, synonym, or description.
get_target_disease_associations
Get target-disease associations with evidence scores.
get_disease_targets_summary
Get prioritized targets associated with a disease.
get_target_details
Get comprehensive target information.
get_disease_details
Get comprehensive disease information.